Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation

Fas–Fas ligand (FasL) signaling plays an important role in the development of allergic inflammation, but the cellular and molecular mechanisms are still not well known. By using the bone marrow-derived dendritic cell (BMDC) transfer-induced pulmonary inflammation model, we found that house dust mite...

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Bibliographic Details
Main Authors: Miaomiao Han, Ran Hu, Jingyu Ma, Baohua Zhang, Ce Chen, Huabin Li, Jun Yang, Gonghua Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
Fas
Th2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03045/full