Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis

Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis

Infantile cholestatic hepatopathy (ICH) is a clinical syndrome characterized by the accumulation of cytotoxic bile acids in infancy, leading to serious liver cirrhosis or liver failure. The aetiology of ICH is complicated and some of them is unknown. Regardless of the aetiology, the finial pathology...

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Bibliographic Details
Main Authors: Huan Qin, Ling-ling Zhang, Xiao-li Xiong, Zhi-xia Jiang, Cui-ping Xiao, Lin-li Zhang, Yu-ji Wang, Yun-tao Wu, Yan-yan Qiu, Li-shan Zhou, Su-qi Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
infantile cholestasis
hepatocyte apoptosis
calcium-sensing receptor (CaSR)
Li-Dan-He-Ji (LDHJ)
forsythoside-A
emodin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00156/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00156/full

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