Synaptic Organizers in Alzheimer’s Disease: A Classification Based on Amyloid-β Sensitivity

Synaptic Organizers in Alzheimer’s Disease: A Classification Based on Amyloid-β Sensitivity

Synaptic pathology is one of the major hallmarks observed from the early stage of Alzheimer’s disease (AD), leading to cognitive and memory impairment characteristic of AD patients. Synaptic connectivity and specificity are regulated by multiple trans-bindings between pre- and post-synaptic organize...

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Bibliographic Details
Main Authors: Alfred Kihoon Lee, Husam Khaled, Nicolas Chofflet, Hideto Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Alzheimer’s disease
amyloid-β
synaptic organizers
neurexin
neuroligin
in situ binding assay
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00281/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00281/full

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