PTEN: A Thrifty Gene That Causes Disease in Times of Plenty?

The modern obesity epidemic with associated disorders of metabolism and cancer has been attributed to the presence of “thrifty genes”. In the distant past, these genes helped the organism to improve energy efficiency and store excess energy safely as fat to survive periods of famine, but in the pres...

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Bibliographic Details
Main Author: Ajit Venniyoor
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnut.2020.00081/full