Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein
Coronaviruses are enveloped positive-stranded RNA viruses that replicate in the cytoplasm. To deliver their nucleocapsid into the host cell, they rely on the fusion of their envelope with the host cell membrane. The spike glycoprotein (S) mediates virus entry and is a primary determinant of cell tro...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-06-01
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Series: | Viruses |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4915/4/6/1011 |