Full genome characterization of human influenza A/H3N2 isolates from Asian countries reveals a rare amantadine resistance-conferring mutation and novel PB1-F2 polymorphisms

Full genome characterization of human influenza A/H3N2 isolates from Asian countries reveals a rare amantadine resistance-conferring mutation and novel PB1-F2 polymorphisms

Influenza A viruses evolve at a high rate requiring continuous monitoring to maintain the efficacy of vaccines and antiviral drugs. We performed next generation sequencing analysis of 100 influenza A/H3N2 isolates collected in four Asian countries (Japan, Lebanon, Myanmar, and Vietnam) during 2012-2...

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Main Authors: Hassan eZaraket, Hiroki eKondo, Akinobu eHibino, Ren eYagami, Takashi eOdagiri, Nobuhiro eTakemae, Ryota eTsunekuni, Takehiko eSaito, Japanese Influenza Collaborative Study Group eJapanese Influenza Collaborative Study Group, Yi Yi eMynt, Yadanar eKyaw, Khin Yi Oo, Htay Htay Tin, Nay eLin, Nguyen Phuong Anh, Nguyen Le Khanh Hang, Le Quinh Mai, Mohd Rohaizat eHassan, Yugo eShobugawa, Julian eTang, Ghassan eDbaibo, Reiko eSaito
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Microbiology
Subjects:
evolution
phylogenetic analysis
antiviral
Reassortment
Influenza A/H3N2
PB1-F2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00262/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00262/full

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