Protein Stability of Pyruvate Kinase Isozyme M2 Is Mediated by HAUSP

The ubiquitin–proteasome system (UPS) is responsible for proteasomal degradation, regulating the half-life of the protein. Deubiquitinating enzymes (DUBs) are components of the UPS and inhibit degradation by removing ubiquitins from protein substrates. Herpesvirus-associated ubiquitin-specific prote...

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Bibliographic Details
Main Authors: Hae-Seul Choi, Chang-Zhu Pei, Jun-Hyeok Park, Soo-Yeon Kim, Seung-Yeon Song, Gyeong-Jin Shin, Kwang-Hyun Baek
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/6/1548