The epigenetic regulator G9a attenuates stress-induced resistance and metabolic transcriptional programs across different stressors and species

Abstract Background Resistance and tolerance are two coexisting defense strategies for fighting infections. Resistance is mediated by signaling pathways that induce transcriptional activation of resistance factors that directly eliminate the pathogen. Tolerance refers to adaptations that limit the h...

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Bibliographic Details
Main Authors: Human Riahi, Michaela Fenckova, Kayla J. Goruk, Annette Schenck, Jamie M. Kramer
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Biology
Subjects:
G9a
Online Access:https://doi.org/10.1186/s12915-021-01025-0