Adolescent Intermittent Ethanol Exposure Effects on Kappa Opioid Receptor Mediated Dopamine Transmission: Sex and Age of Exposure Matter

Adolescent Intermittent Ethanol Exposure Effects on Kappa Opioid Receptor Mediated Dopamine Transmission: Sex and Age of Exposure Matter

Underage alcohol drinking increases the risk of developing alcohol use disorder (AUD). In rodents, adolescent ethanol exposure augments ethanol consumption and anxiety-like behavior while reducing social interaction. However, the underlying mechanisms driving these adaptations are unclear. The dopam...

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Bibliographic Details
Main Authors: Mary B. Spodnick, Raymond T. Amirault, Trevor T. Towner, Elena I. Varlinskaya, Linda P. Spear, Anushree N. Karkhanis
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Brain Sciences
Subjects:
adolescent intermittent ethanol exposure
dopamine
kappa opioid receptors
nucleus accumbens
Online Access:https://www.mdpi.com/2076-3425/10/8/472

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https://www.mdpi.com/2076-3425/10/8/472

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