Mendelian randomization analysis using mixture models for robust and efficient estimation of causal effects

Mendelian randomization (MR) is a powerful and widely used method for causal inference leveraging genetic information. Here, the authors develop MRMix, an MR method using mixture models for more robust and efficient estimation of causal effects.

Bibliographic Details
Main Authors: Guanghao Qi, Nilanjan Chatterjee
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09432-2