Around and beyond 53BP1 Nuclear Bodies

Around and beyond 53BP1 Nuclear Bodies

Within the nucleus, sub-nuclear domains define territories where specific functions occur. Nuclear bodies (NBs) are dynamic structures that concentrate nuclear factors and that can be observed microscopically. Recently, NBs containing the p53 binding protein 1 (53BP1), a key component of the DNA dam...

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Bibliographic Details
Main Authors: Anne Fernandez-Vidal, Julien Vignard, Gladys Mirey
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
53BP1
nuclear bodies
DNA damage
replication stress
common fragile sites
genetic instability
cancer
Online Access:https://www.mdpi.com/1422-0067/18/12/2611

Internet

https://www.mdpi.com/1422-0067/18/12/2611

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