Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets

Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets

The cellular kinases inhibitory-κB kinase (IKK) α and Nuclear Factor-κB (NF-κB)-inducing kinase (NIK) are well recognised as key central regulators and drivers of the non-canonical NF-κB cascade and as such dictate the initiation and development of d...

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Bibliographic Details
Main Authors: Andrew Paul, Joanne Edwards, Christopher Pepper, Simon Mackay
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cells
Subjects:
inhibitory-κB kinase (IKK) α
Nuclear Factor-κB (NF-κB)
NF-κB-inducing kinase (NIK)
cancer
inflammation
small molecule kinase inhibitor
Online Access:http://www.mdpi.com/2073-4409/7/10/176

Internet

http://www.mdpi.com/2073-4409/7/10/176

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