Molecular mechanism of interactions between ACAD9 and binding partners in mitochondrial respiratory complex I assembly

Molecular mechanism of interactions between ACAD9 and binding partners in mitochondrial respiratory complex I assembly

Summary: The dual function protein ACAD9 catalyzes α,β-dehydrogenation of fatty acyl-CoA thioesters in fatty acid β-oxidation and is an essential chaperone for mitochondrial respiratory complex I (CI) assembly. ACAD9, ECSIT, and NDUFAF1 interact to form the core mitochondrial CI assembly complex. Cu...

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Bibliographic Details
Main Authors: Chuanwu Xia, Baoying Lou, Zhuji Fu, Al-Walid Mohsen, Anna L. Shen, Jerry Vockley, Jung-Ja P. Kim
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Structural biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221011214

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221011214

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