Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour

Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour

Cells naturally produce mitochondrial reactive oxygen species (mROS), but the in vivo pathophysiological significance has long remained controversial. Within the brain, astrocyte-derived mROS physiologically regulate behaviour and are produced at one order of magnitude faster than in neurons. Howeve...

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Bibliographic Details
Main Authors: Carlos Vicente-Gutierrez, Nicolo Bonora, Daniel Jimenez-Blasco, Irene Lopez-Fabuel, Georgina Bates, Michael P. Murphy, Angeles Almeida, Juan P. Bolaños
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
Mitochondria
ROS
Neuron
Astrocyte
Signallling
In vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000653

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http://www.sciencedirect.com/science/article/pii/S2213231721000653

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