Transient and Efficient Vascular Permeability Window for Adjuvant Drug Delivery Triggered by Microbeam Radiation

Transient and Efficient Vascular Permeability Window for Adjuvant Drug Delivery Triggered by Microbeam Radiation

Background: Microbeam Radiation Therapy (MRT) induces a transient vascular permeability window, which offers a novel drug-delivery system for the preferential accumulation of therapeutic compounds in tumors. MRT is a preclinical cancer treatment modality that spatially fractionates synchrotron X-ray...

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Bibliographic Details
Main Authors: Sarah Sabatasso, Cristian Fernandez-Palomo, Ruslan Hlushchuk, Jennifer Fazzari, Stefan Tschanz, Paolo Pellicioli, Michael Krisch, Jean A. Laissue, Valentin Djonov
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
vascular permeability
drug delivery system
microbeam radiation therapy (MRT)
Chicken Chorioallantoic Membrane (CAM)
U-87 Glioblastoma
Online Access:https://www.mdpi.com/2072-6694/13/9/2103

Internet

https://www.mdpi.com/2072-6694/13/9/2103

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