Heterogeneous response of endothelial cells to insulin-like growth factor 1 treatment is explained by spatially clustered sub-populations
A common strategy to measure the efficacy of drug treatment is the in vitro comparison of ensemble readouts with and without treatment, such as proliferation and cell death. A fundamental assumption underlying this approach is that there exists minimal cell-to-cell variability in the response to a d...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-11-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/11/bio045906 |