Allelic interaction effects of DNA damage and repair genes on the predisposition to age-related cataract.

Age-related cataract (ARC) is a leading cause of visual impairment and blindness worldwide. DNA damage and malfunction of DNA repair are believed to contribute to the pathogenesis of ARC. Aside from increasing age, the risk factors for ARC appear to be rather complex, and one or more gene variations...

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Bibliographic Details
Main Authors: Mei Yang, Junfang Zhang, Shu Su, Bai Qin, Lihua Kang, Rongrong Zhu, Huaijin Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5915686?pdf=render