High expression of ACE2 and TMPRSS2 and clinical characteristics of COVID-19 in colorectal cancer patients

Abstract Little is known of the patterns of expression of ACE2 and TMPRSS2 or the clinical characteristics of COVID-19 in patients with COVID-19 and colorectal cancer. We found in both bulk and single-cell RNA-seq profiles that ACE2 and TMPRSS2 were expressed at high levels on tumor and normal color...

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Bibliographic Details
Main Authors: Chao Liu, Kai Wang, Min Zhang, Xiaoyu Hu, Tian Hu, Yumei Liu, Qinyong Hu, Shikai Wu, Jinbo Yue
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-020-00139-y