Molecular dynamics simulations of DNA-free and DNA-bound TAL effectors.

TAL (transcriptional activator-like) effectors (TALEs) are DNA-binding proteins, containing a modular central domain that recognizes specific DNA sequences. Recently, the crystallographic studies of TALEs revealed the structure of DNA-recognition domain. In this article, molecular dynamics (MD) simu...

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Bibliographic Details
Main Authors: Hua Wan, Jian-ping Hu, Kang-shun Li, Xu-hong Tian, Shan Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24130757/pdf/?tool=EBI