Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity.
RdCVF and RdCVF2, encoded by the nucleoredoxin-like genes NXNL1 and NXNL2, are trophic factors with therapeutic potential that are involved in cone photoreceptor survival. Studying how their expression is regulated in the retina has implications for understanding both their activity and the mechanis...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-10-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2951342?pdf=render |