Tissue-Specific Sample Dilution: An Important Parameter to Optimise Prior to Untargeted LC-MS Metabolomics

When developing a sample preparation protocol for LC−MS untargeted metabolomics of a new sample matrix unfamiliar to the laboratory, selection of a suitable injection concentration is rarely described. Here we developed a simple workflow to address this issue prior to untargeted LC&#87...

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Bibliographic Details
Main Authors: Zhanxuan E. Wu, Marlena C. Kruger, Garth J.S. Cooper, Sally D. Poppitt, Karl Fraser
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/9/7/124