Population Bottlenecks and Intra-host Evolution During Human-to-Human Transmission of SARS-CoV-2

Population Bottlenecks and Intra-host Evolution During Human-to-Human Transmission of SARS-CoV-2

The emergence of the novel human coronavirus, SARS-CoV-2, causes a global COVID-19 (coronavirus disease 2019) pandemic. Here, we have characterized and compared viral populations of SARS-CoV-2 among COVID-19 patients within and across households. Our work showed an active viral replication activity...

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Bibliographic Details
Main Authors: Daxi Wang, Yanqun Wang, Wanying Sun, Lu Zhang, Jingkai Ji, Zhaoyong Zhang, Xinyi Cheng, Yimin Li, Fei Xiao, Airu Zhu, Bei Zhong, Shicong Ruan, Jiandong Li, Peidi Ren, Zhihua Ou, Minfeng Xiao, Min Li, Ziqing Deng, Huanzi Zhong, Fuqiang Li, Wen-jing Wang, Yongwei Zhang, Weijun Chen, Shida Zhu, Xun Xu, Xin Jin, Jingxian Zhao, Nanshan Zhong, Wenwei Zhang, Jincun Zhao, Junhua Li, Yonghao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
SARS-CoV-2
population bottleneck
intra-host variation
human to human transmission
evolution
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.585358/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.585358/full

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