A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis.

Sepsis, a life-threatening systemic inflammatory response syndrome induced by infection, is widely studied using laboratory animal models. While cecal-ligation and puncture (CLP) is considered the gold standard model for sepsis research, it may not be preferable for experiments comparing animals of...

Full description

Bibliographic Details
Main Authors: Marlene E Starr, Allison M Steele, Mizuki Saito, Bill J Hacker, B Mark Evers, Hiroshi Saito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4274114?pdf=render