A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis.
Sepsis, a life-threatening systemic inflammatory response syndrome induced by infection, is widely studied using laboratory animal models. While cecal-ligation and puncture (CLP) is considered the gold standard model for sepsis research, it may not be preferable for experiments comparing animals of...
Main Authors: | Marlene E Starr, Allison M Steele, Mizuki Saito, Bill J Hacker, B Mark Evers, Hiroshi Saito |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4274114?pdf=render |
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