The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters.

The Ty1 retrotransposons present in the genome of Saccharomyces cerevisiae belong to the large class of mobile genetic elements that replicate via an RNA intermediary and constitute a significant portion of most eukaryotic genomes. The retromobility of Ty1 is regulated by numerous host factors, incl...

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Bibliographic Details
Main Authors: Alicia C Salinero, Elisabeth R Knoll, Z Iris Zhu, David Landsman, M Joan Curcio, Randall H Morse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5834202?pdf=render