Changes in gene expression and cellular architecture in an ovarian cancer progression model.

Ovarian cancer is the fifth leading cause of cancer deaths among women. Early stage disease often remains undetected due the lack of symptoms and reliable biomarkers. The identification of early genetic changes could provide insights into novel signaling pathways that may be exploited for early dete...

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Bibliographic Details
Main Authors: Amy L Creekmore, William T Silkworth, Daniela Cimini, Roderick V Jensen, Paul C Roberts, Eva M Schmelz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048403?pdf=render