Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations
<p>Abstract</p> <p>Background</p> <p>DNA polymerase ε (Pol ε) is essential for S-phase replication, DNA damage repair and checkpoint control in yeast. A <it>pol2-Y831A </it>mutation leading to a tyrosine to alanine change in the Pol ε active site does not ca...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2004-05-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/2/11 |