Scoping review of biological treatment of deficiency of interleukin-36 receptor antagonist (DITRA) in children and adolescents

Scoping review of biological treatment of deficiency of interleukin-36 receptor antagonist (DITRA) in children and adolescents

Abstract Background Deficiency of interleukin-36 receptor antagonist (DITRA) is a life threatening monogenic autoinflammatory disease caused by loss of function mutations in the IL36RN gene. Affected patients develop recurrent episodes of generalized pustular psoriasis (GPP) with systemic inflammati...

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Bibliographic Details
Main Authors: Toni Hospach, Fabian Glowatzki, Friederike Blankenburg, Dennis Conzelmann, Christian Stirnkorb, Chris Sandra Müllerschön, Peter von den Driesch, Lisa Maria Köhler, Meino Rohlfs, Christoph Klein, Fabian Hauck
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Generalized pustular psoriasis (GPP)
IL36RN
Autoinflammation
DITRA
Deficiency of interleukin-36 receptor antagonist
Monogenic disease
Online Access:http://link.springer.com/article/10.1186/s12969-019-0338-1

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http://link.springer.com/article/10.1186/s12969-019-0338-1

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