Canalization of the evolutionary trajectory of the human influenza virus

<p>Abstract</p> <p>Background</p> <p>Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. However, despite strong pressure to evolve away from human immunity and to diversify in antigenic phenotype, H3N2 influenza...

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Bibliographic Details
Main Authors: Bedford Trevor, Rambaut Andrew, Pascual Mercedes
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/10/38