Exosome Released FZD10 Increases Ki-67 Expression via Phospho-ERK1/2 in Colorectal and Gastric Cancer

Exosome Released FZD10 Increases Ki-67 Expression via Phospho-ERK1/2 in Colorectal and Gastric Cancer

Frizzled (FZD) proteins are primary receptors for Wnt signaling that activates the mitogen-activated protein kinase (MAPK) pathways. Dysfunction of Wnt signals with consequently abnormal activation of MAPK3 pathways was found in colorectal cancer (CRC) and gastric cancer (GC). Upregulation of FZD10...

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Bibliographic Details
Main Authors: Maria Principia Scavo, Federica Rizzi, Nicoletta Depalo, Raffaele Armentano, Sergio Coletta, Grazia Serino, Elisabetta Fanizza, Pasqua Letizia Pesole, Alessandra Cervellera, Nicola Carella, Maria Lucia Curri, Gianluigi Giannelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
FZD10
MAPK/ERK
Ki-67
exosomes
colorectal cancer
gastric cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.730093/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.730093/full

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