LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice[S]

LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice[S]

A key step in plasma HDL maturation from discoidal to spherical particles is the esterification of cholesterol to cholesteryl ester, which is catalyzed by LCAT. HDL-like lipoproteins in cerebrospinal fluid (CSF) are also spherical, whereas nascent lipoprotein particles secreted from astrocytes are d...

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Bibliographic Details
Main Authors: Sophie Stukas, Lita Freeman, Michael Lee, Anna Wilkinson, Alice Ossoli, Boris Vaisman, Stephen Demosky, Jeniffer Chan, Veronica Hirsch-Reinshagen, Alan T. Remaley, Cheryl L. Wellington
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Journal of Lipid Research
Subjects:
lecithin:cholesterol acyltransferase
high density lipoprotein metabolism
apolipoproteins
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353359

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520353359

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