Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres

Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres

Summary: Acquisition of replicative immortality is currently regarded as essential for malignant transformation. This is achieved by activating a telomere lengthening mechanism (TLM), either telomerase or alternative lengthening of telomeres, to counter normal telomere attrition. However, a substant...

Full description

Bibliographic Details
Main Authors: Rebecca A. Dagg, Hilda A. Pickett, Axel A. Neumann, Christine E. Napier, Jeremy D. Henson, Erdahl T. Teber, Jonathan W. Arthur, C. Patrick Reynolds, Jayne Murray, Michelle Haber, Alexander P. Sobinoff, Loretta M.S. Lau, Roger R. Reddel
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717307611

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717307611

Similar Items