Independent and Combined Effects of Telomere Shortening and mtDNA<sup>4977</sup> Deletion on Long-term Outcomes of Patients with Coronary Artery Disease

Independent and Combined Effects of Telomere Shortening and mtDNA<sup>4977</sup> Deletion on Long-term Outcomes of Patients with Coronary Artery Disease

Aging is one of the main risk factors for cardiovascular disease, resulting in a progressive organ and cell decline. This study evaluated a possible joint impact of two emerging hallmarks of aging, leucocyte telomere length (LTL) and common mitochondrial DNA deletion (mtDNA<sup>4977</sup>...

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Bibliographic Details
Main Authors: Cecilia Vecoli, Andrea Borghini, Silvia Pulignani, Antonella Mercuri, Stefano Turchi, Eugenio Picano, Maria Grazia Andreassi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
major adverse cardiac events
all-cause mortality
leucocyte telomere length
mtdna<sup>4977</sup> common deletion
coronary artery disease
Online Access:https://www.mdpi.com/1422-0067/20/21/5508

Internet

https://www.mdpi.com/1422-0067/20/21/5508

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