Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

Abstract Background Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal. Dysfunction in skeletal muscle metabolism especially during obesity contributes to the insulin resistance. Astaxanthin (AX), a natural antioxidant, has been shown to ameliorate hepatic insulin resistan...

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Bibliographic Details
Main Authors: Yasuhiro Nishida, Allah Nawaz, Tomonobu Kado, Akiko Takikawa, Yoshiko Igarashi, Yasuhiro Onogi, Tsutomu Wada, Toshiyasu Sasaoka, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Kumpei Tokuyama, Isao Usui, Takashi Nakagawa, Shiho Fujisaka, Yagi Kunimasa, Kazuyuki Tobe
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Astaxanthin
Mitchondrial biogenesis
Exercise‐endurance
Skeletal muscle remodeling
AMPK activation
insulin resistance
Online Access:https://doi.org/10.1002/jcsm.12530

Internet

https://doi.org/10.1002/jcsm.12530

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