Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.

Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.

BACKGROUND:Non-cirrhotic idiopathic portal hypertension (NCIPH) is characterized by splenomegaly, anemia and portal hypertension, while liver function is preserved. However, no animal models have been established yet. This study assessed a rat model of NCIPH and characterized the hemodynamics, and c...

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Bibliographic Details
Main Authors: Sabine Klein, Christian Hinüber, Kanishka Hittatiya, Robert Schierwagen, Frank Erhard Uschner, Christian P Strassburg, Hans-Peter Fischer, Ulrich Spengler, Jonel Trebicka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5010239?pdf=render

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http://europepmc.org/articles/PMC5010239?pdf=render

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