The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation

The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation

Background: Polycythemia vera (PV) is a refractory hematological disease that lack of effective therapy. Chinese traditional medicine Longchai Jiangxue formula (LCJX) has showed the powerful effects on PV. However, the active ingredients and mechanisms of this formula have not been elucidated. We ex...

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Bibliographic Details
Main Authors: Jing Ming, Weiyi Liu, Hongwei Wu, Yujin Li, Erpeng Yang, Ziqing Wang, Haiyan Xiao, Richeng Quan, Xiaomei Hu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Longchai Jiangxue formula
UPLC/Q-TOF-MS/MS
Network pharmacology
Active ingredient
Polycythemia vera
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221005497

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http://www.sciencedirect.com/science/article/pii/S0753332221005497

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