Arthritis induces early bone high turnover, structural degradation and mechanical weakness.

Arthritis induces early bone high turnover, structural degradation and mechanical weakness.

We have previously found in the chronic SKG mouse model of arthritis that long standing (5 and 8 months) inflammation directly leads to high collagen bone turnover, disorganization of the collagen network, disturbed bone microstructure and degradation of bone biomechanical properties. The main goal...

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Bibliographic Details
Main Authors: Bruno Vidal, Rita Cascão, Ana Catarina Vale, Inês Cavaleiro, Maria Fátima Vaz, José Américo Almeida Brito, Helena Canhão, João Eurico Fonseca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4305284?pdf=render

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http://europepmc.org/articles/PMC4305284?pdf=render

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