Ly9 (CD229) cell surface receptor is crucial for the development of spontaneous autoantibody production to nuclear antigens

Ly9 (CD229) cell surface receptor is crucial for the development of spontaneous autoantibody production to nuclear antigens

The Signaling Lymphocyte Activation Molecule Family (SLAMF) genes, which encode cell-surface receptors that modulate innate and adaptive immune responses, lay within a genomic region of human and mouse chromosome 1 that confers a predisposition for the development of systemic lupus erythematosus (SL...

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Bibliographic Details
Main Authors: Jose ede Salort, Marta eCuenca, Cox eTerhorst, Pablo eEngel, Xavier eRomero
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Disease Susceptibility
systemic lupus erythematosus (SLE)
SLAM family receptors
Ly9 (CD229/SLAMF3)
Anti-DNA autoantibodies
Murine Lupus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00225/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00225/full

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