How do thiazide and thiazide-like diuretics lower blood pressure?

Thiazide diuretics are widely used for the treatment of hypertension, but the mechanism by which these drugs lower blood pressure in the long term remains unknown. This article reviews current knowledge about the hypotensive actions of thiazides and thiazide-like diuretics and discusses possible mec...

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Bibliographic Details
Main Author: Alun D Hughes
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2004.034