Towards the application of Tc toxins as a universal protein translocation system

Tc toxins are a major class of bacterial toxin translocation systems that inject toxic enzymes into target cells. Here the authors present functional and structural data showing that the toxic enzyme can be replaced by other small proteins and identify prerequisites required for successful transloca...

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Bibliographic Details
Main Authors: Daniel Roderer, Evelyn Schubert, Oleg Sitsel, Stefan Raunser
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13253-8