Prediction of severity and subtype of fibrosing disease using model informed by inflammation and extracellular matrix gene index.

Fibrosis is a chronic disease with heterogeneous clinical presentation, rate of progression, and occurrence of comorbidities. Systemic sclerosis (scleroderma, SSc) is a rare rheumatic autoimmune disease that encompasses several aspects of fibrosis, including highly variable fibrotic manifestation an...

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Bibliographic Details
Main Authors: Amin M Cheikhi, Zariel I Johnson, Dana R Julian, Sarah Wheeler, Carol Feghali-Bostwick, Yvette P Conley, James Lyons-Weiler, Cecelia C Yates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240986