ADAR Enzyme and miRNA Story: A Nucleotide that Can Make the Difference

ADAR Enzyme and miRNA Story: A Nucleotide that Can Make the Difference

Adenosine deaminase acting on RNA (ADAR) enzymes convert adenosine (A) to inosine (I) in double-stranded (ds) RNAs. Since Inosine is read as Guanosine, the biological consequence of ADAR enzyme activity is an A/G conversion within RNA molecules. A-to-I editing events can occur on both coding and non...

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Bibliographic Details
Main Authors: Sara Tomaselli, Barbara Bonamassa, Anna Alisi, Valerio Nobili, Franco Locatelli, Angela Gallo
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
Adenosine deaminase acting on RNA (ADAR)
A-to-I RNA editing
double-stranded RNA (dsRNA)
non-coding sequence
Online Access:http://www.mdpi.com/1422-0067/14/11/22796

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http://www.mdpi.com/1422-0067/14/11/22796

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