Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

Abstract Background Human bone marrow-derived mesenchymal stem/stromal cells (hBM MSCs) have multiple functions, critical for skeletal formation and function. Their functional heterogeneity, however, represents a major challenge for their isolation and in developing potency and release assays to pre...

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Bibliographic Details
Main Authors: Alison T. Merryweather-Clarke, David Cook, Barbara Joo Lara, Peng Hua, Emmanouela Repapi, Neil Ashley, Shiang Y. Lim, Suzanne M. Watt
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem/stromal cells
Osteogenesis
Vascular supportive capacity
RNAseq
Clonal analysis
CFU-F
Online Access:http://link.springer.com/article/10.1186/s13287-018-1095-7

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http://link.springer.com/article/10.1186/s13287-018-1095-7

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