High binding affinity of electronegative LDL to human aortic proteoglycans depends on its aggregation level[S]

High binding affinity of electronegative LDL to human aortic proteoglycans depends on its aggregation level[S]

Electronegative LDL [LDL(−)] is an atherogenic subfraction of plasma LDL that has increased apolipoprotein E (apoE) and apoC-III content, high density, and increased susceptibility to aggregation. These characteristics suggest that LDL(−) could bind to proteoglycans (PGs); therefore, our aim was to...

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Bibliographic Details
Main Authors: Cristina Bancells, Sònia Benítez, Matti Jauhiainen, Jordi Ordóñez-Llanos, Petri T. Kovanen, Sandra Villegas, José Luis Sánchez-Quesada, Katariina O¨o¨rni
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Journal of Lipid Research
Subjects:
glycosaminoglycans
lipoprotein aggregation
sphingomyelinase
phospholipase C
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520308889

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520308889

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