High binding affinity of electronegative LDL to human aortic proteoglycans depends on its aggregation level[S]
Electronegative LDL [LDL(−)] is an atherogenic subfraction of plasma LDL that has increased apolipoprotein E (apoE) and apoC-III content, high density, and increased susceptibility to aggregation. These characteristics suggest that LDL(−) could bind to proteoglycans (PGs); therefore, our aim was to...
Main Authors: | Cristina Bancells, Sònia Benítez, Matti Jauhiainen, Jordi Ordóñez-Llanos, Petri T. Kovanen, Sandra Villegas, José Luis Sánchez-Quesada, Katariina O¨o¨rni |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2009-03-01
|
Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520308889 |
Similar Items
-
HDL and electronegative LDL exchange anti- and pro-inflammatory properties
by: Cristina Bancells, et al.
Published: (2010-10-01) -
Aggregation, fusion, and vesicle formation of modified low density lipoprotein particles: molecular mechanisms and effects on matrix interactions
by: Katariina Öörni, et al.
Published: (2000-11-01) -
The Induction of Cytokine Release in Monocytes by Electronegative Low-Density Lipoprotein (LDL) Is Related to Its Higher Ceramide Content than Native LDL
by: Jordi Ordoñez-Llanos, et al.
Published: (2013-01-01) -
Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL
by: C. Daniel Meyers, et al.
Published: (2003-11-01) -
Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis
by: Douglas W. Petcoff, et al.
Published: (2008-11-01)