A Novel Method for Controlled Gene Expression via Combined Bleomycin and Plasmid DNA Electrotransfer

A Novel Method for Controlled Gene Expression via Combined Bleomycin and Plasmid DNA Electrotransfer

Electrochemotherapy is an efficient method for the local treatment of cutaneous and subcutaneous metastases, but its efficacy as a systemic treatment remains low. The application of gene electrotransfer (GET) to transfer DNA coding for immune system modulating molecules could allow for a systemic ef...

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Bibliographic Details
Main Authors: Sonam Chopra, Paulius Ruzgys, Milda Jakutaviciute, Aiste Rimgailaite, Diana Navickaitė, Saulius Satkauskas
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
gene electrotransfer
cell death
bleomycin
plasmid DNA
transfection
cytotoxic effect
Online Access:https://www.mdpi.com/1422-0067/20/16/4047

Internet

https://www.mdpi.com/1422-0067/20/16/4047

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