Interleukin-1 signaling induced by Streptococcus suis serotype 2 is strain-dependent and contributes to bacterial clearance and inflammation during systemic disease in a mouse model of infection

Interleukin-1 signaling induced by Streptococcus suis serotype 2 is strain-dependent and contributes to bacterial clearance and inflammation during systemic disease in a mouse model of infection

Abstract Streptococcus suis serotype 2 is an important porcine pathogen and zoonotic agent causing sudden death, septic shock and meningitis, with exacerbated inflammation being a hallmark of the infection. A rapid, effective and balanced innate immune response against S. suis is critical to control...

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Bibliographic Details
Main Authors: Agustina Lavagna, Jean-Philippe Auger, Audrey Dumesnil, David Roy, Stephen E. Girardin, Nicolas Gisch, Mariela Segura, Marcelo Gottschalk
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0670-y

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http://link.springer.com/article/10.1186/s13567-019-0670-y

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