Neuroprotection by Wld S depends on retinal ganglion cell type and age in glaucoma

Abstract Background Early challenges to axonal physiology, active transport, and ultrastructure are endemic to age-related neurodegenerative disorders, including those affecting the optic nerve. Chief among these, glaucoma causes irreversible vision loss through sensitivity to intraocular pressure (...

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Bibliographic Details
Main Authors: Michael L. Risner, Silvia Pasini, Nolan R. McGrady, Karis B. D’Alessandro, Vincent Yao, Melissa L. Cooper, David J. Calkins
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-021-00459-y