Polymorphism of the Transferrin Gene in Eye Diseases: Keratoconus and Fuchs Endothelial Corneal Dystrophy

Oxidative stress may play a role in the pathogenesis of keratoconus (KC) and Fuchs endothelial corneal dystrophy (FECD). Iron may promote the stress by the Fenton reaction, so its homeostasis should be strictly controlled. Transferrin is essential for iron homeostasis because it transports iron from...

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Main Authors: Katarzyna A. Wójcik, Ewelina Synowiec, Manuel P. Jiménez-García, Anna Kaminska, Piotr Polakowski, Janusz Blasiak, Jerzy Szaflik, Jacek P. Szaflik
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/247438