Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network.

Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network.

Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied here a Bayesian selectivity model to predict hundred...

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Bibliographic Details
Main Authors: Aartjan J W te Velthuis, Philippe A Sakalis, Donald A Fowler, Christoph P Bagowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283644/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283644/?tool=EBI

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